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Kanzius Cancer Cure?

Discussion in 'BBS Hangout' started by Cohen, Apr 13, 2008.

  1. KingCheetah

    KingCheetah Atomic Playboy
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    They can't test it on him yet -- against the law.
     
  2. Mr. Brightside

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    But if he has a prototype of his own machine, what is stopping him from testing it on himself?
     
  3. DaDakota

    DaDakota Balance wins
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    He has luekemia, which is not a tumor, but a blood disorder....so right now they have not gotten the ability to get the nanotech molecules into the affected blood cells etc...

    Right now it is more tumor specific.......I think it has massive ramifications.

    DD
     
  4. Two Sandwiches

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    Good point about the sedation Meggo....

    Anyways., I asked one of my radiologists about this today. I was very vague. I just said, "So, have you heard of this Kanzius guy?" He said yes, so I asked what he thought.

    He said he thinks it's interesting, but seemed skeptical it would work in humans. I asked him if he thought they would ever find a binding agent to just specifically bind to cancer cells, and he said that yes, that should be something they are able to do.

    I still find this very interesting. God, I wish I was a researcher on this project.
     
  5. Mack

    Mack Member

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    It's a great story, but I think the really difficult part will be targeting the cancer cells. From the show, it sounds like they inject the nano-particles directly into the tumor, then irradiate it, killing the tumor. But if the cancer cells have metastasized, you can't do that anymore.

    If this technology works, and you can find a way to target the nano-particles specifically to bacteria, virus, parasite, etc. (with antibodies maybe), you could potentially treat things ranging from MRSA, HIV, malaria, tuberculosis, the flu, even acne and obesity :eek:
     
  6. Storm Surge

    Storm Surge Rookie

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    so...not only will this Kanzius guy save millions of people from cancer, he is going to save the entire world population from running out of fossil fuels?

    Is this guy THE MESSIAH???
     
  7. hooroo

    hooroo Member

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    the injected nanoparticle thing sounds familiar. i think there are a couple of australian biotech companies with similiar products. they haven't gone to market but have been trialled on humans for several years now. except the ceramic nanoparticles are radioactive with half life that is days long.
     
  8. Two Sandwiches

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    It's not irradiating, since the radio waves are not radiation. They do not ionize(at least that's what they're saying), therefore, in theory, they cause no harmful effects on the person. I know of a few doctors who do not believe in this no harmful effects thing, and I personally think there is a small risk that has not been correlated to anything. You are, afterall, putting energy into the body that was never there. That's got to have some sort of risk.

    Anyways, the "binding agent" is the tricky part. I think it'd be hard for them to do - they'd probably have to find a specific binding agent for each type of cancer...much like nuclear medicine studies, and that would take some time probably. I think that's the only obstacle in them testing on humans right now.

    As far as treating metastases, when cancer metastasizes, it keeps the same makeup of it's primary cancer. That's how you can tell colon cancer has metastasized into the liver...it exudes colon characteristics. This is how they would use this one binding agent to theoretically treat metastases.

    You could possibly use the treatment for things like MRSA, the flu, etc., but those types of things that aren't life threatening probably do not warrant killing body cells. HIV, though, I don't know if that's a possibility, but it's a very interesting question.

    It seems some of these doctors think that they can find these binding agents. This is got my nerd factor up to about 100000.
     
  9. Two Sandwiches

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    This sounds similar to bachytherapy.

    The other thing I forgot to say is that on an economic level, they say they want to make the city of Erie the center of the manufacturing for these machines. In the future, if this works on humans, they say it could have an economic impact of up to 10 - 15 billion dollars a year. THAT'S HUGE. It's probably overestimating a little, but that's significant.

    Dr. Steven Curley will publish his findings in the Fall, apparently, and says that this thing may be as close to two years from testing on humans. I'll stay tuned....

    Kanzius Cancer Research Site
     
  10. Mack

    Mack Member

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    Yeah, it seems like the limitation of the current technique is identification of the cancer cells. On 60 Minutes they showed the test rat with liver cancer. They had to manually inject nano-particles into the tumor and "zap" it. If cancer cells metastasize, you can't just inject nano-particles into all of them can you? Of course, if you had a way to deliver the nano-particles to ONLY the cancer cells that would solve the problem.

    As far as treating MRSA, tuberculosis, malaria, the flu, HIV, etc. If by chance scientists were able to discover a way to specifically target nano-particles to the bacteria / virus / parasites that cause these diseases, that's where the beauty of the Kanzius technique would be evident. It wouldn't kill body cells, it would only kill the bacteria that cause tuberculosis/MRSA, or the parasites that cause malaria, or the viruses that cause the flu or HIV. Amazing.
     
  11. Two Sandwiches

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    Exactly. The current limitation is that you can't get something to pair the nanoparticles with that identifies the cancer cells. If you can do that, you can inject the particles with the "binding agent", as I call it, directly into the bloodstream through an IV. That's where the beauty of it lies. You inject it through an IV, the particles find the cancer cells themselves, attach to them, then you heat them till the cells are dead.

    What I was saying earlier is that when cancer cells metastasize, they still retain the qualities of the primary cancer site; therefore, if you can find something that will bind to these cells, they will not only bind to the primary cancer site, but they'll bind to the site of metastasis, destroying seemingly all cancer in the body.

    My point about the flu/MRSA/etc. is that these types of things are curable usually. A person can recover from them. You can't always just kill off cells and have them reproduce back. Because of that, I think there is a bit of hesitance when it comes to using this technique in those things.

    Really, we're just at the tip of this thing though. It could not work at all, or it could (on the very extreme flip side) cure all diseases out there.
     
  12. Phreak3

    Phreak3 Member

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    So, if they don't find a way to "bind" nanoparticles to the metastic cancer cells, then this whole thing would be kind of a failure right? ..'cuz if all it's good for is to remove tumors.. well surgeons can already cut tumors out.. no difference there.
     
  13. Invisible Fan

    Invisible Fan Member

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    In the future, we'll be able to shrink submarines and put them into people's blood stream. Injections will be delivered by Dennis Quaid.
     
  14. Two Sandwiches

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    Basically. If there is no development that is able to bind the nanoparticles to the cancer cells, then you're left with a minimally invasive way to remove tumors. Still less side affects than cutting it out or therapy.
     
  15. Pest_Ctrl

    Pest_Ctrl Member

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    I would love to believe him, but it just doesn't make sense to me. Radio wave just does not carry enough energy to do anything. I do sincerely wish he would prove me wrong. Then that would be one of the biggest advances in medicine.
     
  16. Pest_Ctrl

    Pest_Ctrl Member

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    The basic idea of recognition of tumor cells would be to coat the gold nanoparticles with some antibodies that specifically target something unique on the surface of the cancer cell. It is easy to attach antibodies onto gold nanoparticles, the hard part is what antibodies to use. The protein that could be expressed on the cancer cell's surface could also appear on regular cells, and is likely to vary from patient to patient, from cancer to cancer. So in the end, a patient might need to get his/her own specialized treatment.

    Call me a skeptic, but radio frequency waves and nanoparticles just don't seem to mix for me. The scale of radio waves are on the order of meters, and that's way too big for the nanoparticles to receive energy from. Also, if/when we can get auto-targeting nanoparticles, there would be a lot of ways to kill the cancer cells. We can just let the nanoparticle also carry some toxin with it, and that will also do the job. The side effects of chemotherapy drugs are usually because they are also toxic to normal cells, but if you can deliver them directly and only to the cancer cells, it is probably going to be much much more effective and with minimal side effects.
     
  17. KingCheetah

    KingCheetah Atomic Playboy
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    In addition to what DD posted he can also get a blood marrow transplant, which I believe he said is planning on doing. I would imagine as a last resort he would be able to test the machine on himself if they have figured out a way to attach the nanoparticles to the cancer cells.

    As for those they say it can't work -- the radio waves are already working to destroy cancer cells in lab rat tumors and the nanoparticles are heated when placed in the machine. The inventor of the nanoparticles said, "Holy ****" when he received word that the things heated up -- he didn't think it would work at all.
     
  18. Two Sandwiches

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    The treatment should vary from cancer to cancer, but not necessarily from patient to patient. The first paragraph you wrote is what I've been saying this whole thread.

    As far as the radio frequency thing, it's already working on rabbits and mice. If it's proven to penetrate deep enough into human tissue, they've got something. The problem, like you and I have said, is finding something that will specifically target the cancer cells, and only the cancer cells.

    As far as the nanoparticles carrying some toxin, remember, they're proposing that the particles be given through an IV injection. If they're toxic, they're going to be generating havoc on the bloodstream as they travel to the tumor. Also, if there's a toxin in them, you risk the nanoparticles destroying the cancer cells and then not stopping...continuing to destroy more, healthy cells, which is kind of the point of this thing

    As far as delivering the chemotherapy drugs directly, that is impossible if there is metastasis. This whole Kanzius treatment plan is to zap out ALL cancer cells, including metastasis. (This is enabled, as I said before, by migrating cancer cells keeping like qualities from the primary cancer tumor) If you're injecting chemo drugs into the nanoparticles to be delivered just to the cancer cells, you're still more than likely going to damage the blood and vessels as the drugs travel through them, thus taking you back to square one.

    I think that heating metal that is only in the affected cells is the most effective way (of these options), because there is little to no extensive risk of a toxin leaking and causing substantial damage to unaffected tissues.
     
  19. WildSweet&Cool

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    I would agree. The metal alone doesn't do any damage to anything, including the cancer. What kills the cancer is the heat that is delivered by the metal once it's exposed to radio waves. Cancer cells can't survive when heated to 42 degrees Celsius (107.6 Fahrenheit).
     
  20. droxford

    droxford Member

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    OLD THREAD BUMP

    Since I first learned of the Kanzius cancer treatment theory, I've been a firm believer that it will one day be the cure for ALL cancer and, quite probably, almost any form of disease (including HIV).

    the Kanzius center has now built a large, human-size radio frequency generator and is having great success with lab animals. They hope to get FDA approval to begin human testing this year.

    I think this article made an error, though. In this treatment, patients are subjected to the gold particles BEFORE being exposed to the radio waves. The gold particles attach themselves to cancer cells and, when the body is exposed to the harmless radio waves, the gold cells heat up, burning away the cancer cells.

    http://www.electroiq.com/index/disp...oninvasive-radio-fields-attack-pancreati.html

    Gold nanoparticles and noninvasive radio fields attack pancreatic carcinoma without collateral damage

    January 17, 2011 - PRNewswire -- The Kanzius Cancer Research Foundation (KCRF) announced that research conducted in the Kanzius/Curley Lab at The University of Texas M.D. Anderson Cancer Center has been published in the December 2010 issue of the American Association of Cancer Research's Clinical Cancer Research journal. The manuscript ("Noninvasive Radiofrequency Field Destruction of Pancreatic Andenocarcinoma Xenografts Treated with Targeted Gold Nanoparticles" can be found under http://www.kanziuscancerresearch.org/research/published_research_manuscripts.illustrates) how Drs. Steven A. Curley and Evan S. Glazer's studies prove that radiofrequency fields can treat pancreatic tumors, which today, kill more than 95% of diagnosed patients. Studies found that noninvasive radiofrequency (RF) fields were effective in controlling relatively large malignant pancreatic tumors. Additionally, this process took place without any injury to surrounding tissue or changes in non-human subject behavior.

    The manuscript describes the process as non-human subjects are exposed to 10 minutes of nonionizing radiofrequency (RF) radiation followed by 36 hours of treatment using targeted gold nanoparticles (AuNP). This revolutionary design shows that the Kanzius RF machine alongside these particular nanoparticles create an effective formula for controlling pancreatic cancer cells. Also read: Gold nanoparticles could 'cook' cancer cells

    "John Kanzius, who created the RF device, once envisioned a cancer treatment that would be both effective and have zero side effects," remarked Curley, Chief of Gastrointestinal Tumor Surgery and Program Director of Multidisciplinary Gastrointestinal Cancer Care at The University of Texas M. D. Anderson Cancer Center. "These experiments demonstrate that the Kanzius RF device controls pancreatic cancer cells without any damage to nearby cells, or normal tissues and organs. We still have a lot of work to do but this is an important proof of principle."

    "These recent findings bring us one step closer to producing an effective, noninvasive cancer treatment that doesn't have the side effects associated with current treatments like chemotherapy and radiation," said Mark Neidig, Executive Director of KCRF. Also read: Nano-particles can lessen cancer drug side effects: Animal tests confirm

    The Kanzius Cancer Research Foundation is a 501(c)(3) non-profit organization with a mission to create national and global awareness of the potentials of the Kanzius Noninvasive Radiowave Cancer Treatment, and to help accelerate the speed at which this research progresses to human trials. For more information about the Kanzius research, visit www.Kanzius.org.
     

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