Ya, I'm curious too. By the reactions, it seems that it's something that plays through out the movie till the end. (like a twist). If so, that just ruined it for me.
Unfortunately, it's the Bruce Willis Sixth Sense spoiler type...however, I don't think that defeats some of the good things about the movie...especially for those Fallout 3 fans... Although the religious overtones were a bit much, I thought the Hughes brother did a fairly good job toward keeping the theme/environment consistent, outside of a few things...still worth a watch imo.