Issued executive order authorized by Ch. 418 1. Every person in Texas shall avoid social gatherings of more than 10 2. Avoid bars, restaurants, food courts, gyms 3. Shall not visit nursing homes, retirement centers unless critical assistance 4. All schools temporarily closed; education does not stop; online or additional educational options Effective midnight tomorrow through midnight April 3rd; could be extended depending on COVID19 in Texas Not a shelter-in-place order
Damn, man. That's a little uncalled for. These are trying times. Let's try and be good to each other. (Edited because what I wrote wasn't very helpful)
FYI roquine: Drug information Access Lexicomp Online here. Copyright 1978-2020 Lexicomp, Inc. All rights reserved. (For additional information see "Chloroquine: Patient drug information" and see "Chloroquine: Pediatric drug information") For abbreviations and symbols that may be used in Lexicomp (show table) Brand Names: Canada TEVA-Chloroquine Pharmacologic Category Aminoquinoline (Antimalarial); Antimalarial Agent Dosing: Adult Note: Each 250 mg of chloroquine phosphate is equivalent to 150 mg of chloroquine base Malaria chemoprophylaxis: Oral: 500 mg (300 mg base) weekly on the same day each week; begin 1 to 2 weeks prior to exposure; continue while in endemic area and for 4 weeks after leaving endemic area (CDC 2018) Malaria treatment, uncomplicated: Oral: 1 g (600 mg base) on day 1, followed by 500 mg (300 mg base) 6-, 24-, and 48 hours after first dose. Note: For treatment of chloroquine-sensitive P. vivax and P. ovale, concomitant therapy with an 8-aminoquinoline (eg, primaquine) is necessary (CDC 2013). Extraintestinal amebiasis: Oral: 1 g (600 mg base) daily for 2 days followed by 500 mg daily (300 mg base) for at least 2 to 3 weeks; may be combined with an intestinal amebicide. Lupus erythematosus (off-label use): Not considered first-line agent (Bezerra 2005; Lesiak 2008). Due to the risk of retinal toxicity, do not exceed a daily dose of 2.3 mg/kg/day of chloroquine phosphate using actual body weight; intermediate doses may be obtained by splitting tablets or eliminating a tablet on certain days of the week (AAO [Marmor 2016]). Dosing: Renal Impairment: Adult There are no dosage adjustments provided in the manufacturer’s labeling; the following guidelines have been used by some clinicians (Aronoff 2007): GFR ≥10 mL/minute: No dosage adjustment necessary. GFR <10 mL/minute: Administer 50% of dose. Hemodialysis, peritoneal dialysis: Administer 50% of dose. Continuous renal replacement therapy (CRRT): No dosage adjustment necessary. Dosing: Hepatic Impairment: Adult There are no dosage adjustments provided in the manufacturer’s labeling; use with caution. Dosing: Pediatric (For additional information see "Chloroquine: Pediatric drug information") Note: Dosage expressed as chloroquine phosphate. Chloroquine phosphate 16.6 mg is equivalent to 10 mg chloroquine base. Malaria: Chemoprophylaxis: Infants, Children, and Adolescents: Oral: 8.3 mg/kg chloroquine phosphate once weekly on the same day each week; maximum dose: 500 mg chloroquine phosphate/dose. Begin 1 to 2 weeks prior to exposure; continue while in endemic area and continue for at least 4 weeks after leaving endemic area (CDC 2014); if suppressive therapy is delayed, double the initial loading dose (16.6 mg/kg, up to 1,000 mg chloroquine phosphate) and administer in 2 divided doses 6 hours apart; continue for 8 weeks after leaving endemic area Treatment, acute attack, uncomplicated: Infants, Children, and Adolescents: Oral: Initial 16.6 mg/kg chloroquine phosphate (maximum initial dose: 1,000 mg chloroquine phosphate); followed by 8.3 mg/kg chloroquine phosphate (maximum dose: 500 mg chloroquine phosphate/dose) administered at 6, 24, and 48 hours after initial dose for a total of 4 doses (CDC 2013) Extraintestinal amebiasis, liver abscess: Children and Adolescents: Limited data available: Oral: 16.6 mg/kg chloroquine phosphate/dose once daily in combination with metronidazole or tinidazole for 21 days followed by paromomycin or iodoquinol; maximum dose: 1,000 mg chloroquine phosphate/dose (Bradley 2015; Seidel 1984; Tony 1992) Dosing: Renal Impairment: Pediatric There are no dosage adjustments provided in the manufacturer’s labeling; in adult patients, dosage adjustment suggested. Dosing: Hepatic Impairment: Pediatric There are no dosage adjustments provided in the manufacturer’s labeling; use with caution. Dosing: Geriatric Refer to adult dosing. Dosage Forms: US Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Tablet, Oral, as phosphate: Generic: 250 mg [equivalent to chloroquine base 150 mg], 500 mg [equivalent to chloroquine base 300 mg] Generic Equivalent Available: US Yes Dosage Forms: Canada Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Tablet, Oral, as phosphate: Generic: 250 mg [equivalent to chloroquine base 150 mg] Administration: Pediatric Oral: Administer with meals to decrease GI upset; chloroquine phosphate tablets have also been mixed with chocolate syrup or enclosed in gelatin capsules to mask the bitter taste Use: Labeled Indications Malaria: Treatment of uncomplicated malaria due to susceptible strains of Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium falciparum; prophylaxis of malaria (in geographic areas where chloroquine resistance is not present). Limitations of use: Chloroquine does not prevent relapses in patients with vivax or ovale malaria (not effective against exoerythrocytic forms). Do not use for the treatment of complicated malaria (high-grade parasitemia and/or complications [eg, cerebral malaria, acute renal failure]) or for malaria prophylaxis in areas where chloroquine resistance occurs (resistance to chloroquine is widespread in P. falciparum and reported in P. vivax). Extraintestinal amebiasis: Treatment of extraintestinal amebiasis. Use: Off-Label: Adult Discoid lupus erythematosus Medication Safety Issues International issues: Aralen [U.S., Mexico] may be confused with Paralen brand name for acetaminophen [Czech Republic] Adverse Reactions Frequency not defined. Cardiovascular: Atrioventricular block, bundle branch block, cardiac arrhythmia, cardiomyopathy, ECG changes (including prolonged QRS and QTc intervals, T-wave inversion, or depression), hypotension, torsades de pointes, ventricular fibrillation, ventricular tachycardia Central nervous system: Agitation, anxiety, confusion, decreased deep tendon reflex, delirium, depression, extrapyramidal reaction (dystonia, dyskinesia, protrusion of the tongue, torticollis), hallucination, headache, insomnia, motor dysfunction (sensorimotor disorder), personality changes, polyneuropathy, psychosis, seizure, suicidal tendencies Dermatologic: Alopecia, bleaching of hair, blue gray skin pigmentation, erythema multiforme, exacerbation of psoriasis, exfoliative dermatitis, lichen planus, pleomorphic rash, pruritus, skin photosensitivity, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria Endocrine & metabolic: Hypoglycemia Gastrointestinal: Abdominal cramps, anorexia, diarrhea, nausea, vomiting Hematologic & oncologic: Agranulocytosis (reversible), aplastic anemia, hemolytic anemia (in G6PD-deficient patients), neutropenia, pancytopenia, thrombocytopenia Hepatic: Hepatitis, increased liver enzymes Hypersensitivity: Anaphylactoid reaction, anaphylaxis, angioedema Immunologic: DRESS syndrome Neuromuscular & skeletal: Myopathy, neuromuscular disease, proximal myopathy Ophthalmic: Accommodation disturbances, blurred vision, corneal opacity (reversible), macular degeneration (may be irreversible), maculopathy (may be irreversible), nocturnal amblyopia, retinopathy (including irreversible changes in some patients' long-term or high-dose therapy), transient scotomata, visual field defects Otic: Deafness (nerve), hearing loss (risk increased in patients with preexisting auditory damage), tinnitus
Finally, acting like a leader. It took him forever. He was quiet for quite a while even as local governments were acting.
We can only control ourselves, we have no power over idiots. This why government always has to step in.
I think the leash has been plenty long for that poster and some of the stuff they are posting hasn't been particularly nice in of itself. I'm not exactly flooding the thread with negative waves. Just thought putting a foot down after page after page of that posters hysterics was called for.
Exactly. Look how much information there is on chloroquine and hydroxychloroquine. Evey single side effect is known and all the dosologies. All the drug -drug reactions. Much safer than using failed Ebola medicines that barely passed the trial phases and have never been used in a wide scale.
Ha mocking the poor NCAA senior athletes who lost their chances to compete for NCAA championship's. You're a real piece of work. One of the most despicable people posting on these forums and quite clearly a terrible human.
Great news! You took all the best measures immediately! Will the expected law breakers be fined or arrested? * the next step should be to put a limit on supermarkets visitors , public transportation (bus, trolley, the tube) and close down airbnbs/hotels.
Nope I am mocking you who are quick to lament the loss of a ncaa championship but are indifferent to the loss of hundred of thousands of humans lives. As long as they arent american lives! Italy can go die.
