It’s not the weight loss peptides but I use TB500/BPC157 and those peptides have been spectacular for injury recovery.
But eventually you'll die and then you can stop. My father been taking medicine for his blood pressure for 4 decades. Don't see why this has to be different. I'm not struggling much with weight and I don't take meds for it, but I've aged past the days of treating my body like a temple. Everything is starting to fall apart. If I can screw in a 2x4 and duct tape some **** together to get me to the finish line, that's what I would do.
The early studies have shown that after significant weight loss on semaglutide, when people stop, they regain 30-40% of the weight they lost on average, as compared to other weight loss programs which tend to regain ALL the weight back, so there is still big benefit for obese people to be on these medicines. Also, while there are bad side effects for some people (usually tummy troubles) there are side effects that are being found out that are really positive. Heart related diseases drop off significantly in the population on semaglutide, more than just the weight loss would normally make it. It also seems to help people with other addictions. While I agree with weight loss being a lifestyle, a significant portion of the population has cravings for food beyond a "normal" person. A friend of mine that started the medicine came up to me about 3 weeks later and was like "is this what normal people feel like? I don't have this constant, gnawing urge to constantly eat anymore.". That's significant and he thought it was life changing. Additionally, if you take a step back and look at the population level health implications, they are massive. 100,000,000 adults in the US are obese. That brings significant health factors, raises healthcare costs for everyone, lowers the life expectancy, all kinds of stuff. If even 1/3 of those people could cure their obesity through these drugs, the social and financial impact would be gigantic.
Financial impact of the pharmaceutical companies. There has to be a solution where we are not constantly marketed terrible food that causes obesity and then marketed drugs that constantly fix it. There has to be more root cause efforts.
That is impressive. I went from 220-190-195 and stuck there for the last year, I really should get to 180 as well, i am 6ft.
I have been taking Mounjaro since February, and have lost 40 lbs. I am also taking metformin in unison. It has helped curb my urge for alcohol too, which has been awesome (drank way too much before getting on this stuff). Have not had very many side effects. Insurance pays 100% of mine too, which is awesome.
https://www.upi.com/Health_News/2024/08/27/Zepbound-price-cut-Lilly/2571724773168/ Eli Lilly, maker of one of the blockbuster GLP-1 weight-loss drug Zepbound, says it will now offer the medication in single-dose vials at half the price currently available to consumers. The new 2.5 milligram (mg) and 5 mg weekly dose vials differ from the standard preloaded injector pens that are used to administer Zepbound (tirzepatide) and competitors such as Wegovy (semaglutide). Instead, patients will use a syringe to withdraw the liquid drug from the vial. A four-week supply of the 2.5 mg vials will be priced at $399, and a similar supply of the 5 mg vials at $529 -- about half what a month's supply of other GLP-1 obesity meds cost. There's one catch: Consumers can only order the new vials by paying out of pocket via LillyDirect, a company platform that coordinates telehealth services and fills prescriptions for patients, the company said in a statement. Lilly said buying the vials direct from the company cuts cost by "removing third-party supply chain entities and allowing patients to access savings directly outside of insurance." According to Lilly, the new, cheaper product fulfills two goals: Widening access to the sometimes tough-to-get meds, and thwarting what it says are potential unsafe copycat versions made by compounding pharmacies. "We are excited to share that the Zepbound single-dose vials are now here, further delivering on our promise to increase supply of Zepbound in the U.S.," Patrik Jonsson, Lilly executive vice president and president of Lilly Cardiometabolic Health and Lilly USA, said in the statement. "These new vials not only help us meet the high demand for our obesity medicine, but also broaden access for patients seeking a safe and effective treatment option." Patients who fall outside of the Zepbound savings card program, those without employer coverage and those who need to pay out-of-pocket can now more easily access the drug, Lilly said.
You need to actually look at its 4-6 year chart. The GLP-1 hype started a few years ago. I still kick myself for not buying this and .... Chipotle stock. And, oh yeah, I got into nVidia late, too, despite living and breathing in PC forums for years and knowing exactly what they were up to. Same with Eli Lilly - tirzepatide phase 3 trials were about 4 years ago (?), I think. That hype's been building forever, but I'm gun-shy when it comes to biotech and relying on phased results on meds that may end up a failure and kill your stock price. lol. The 4-5 year chart on Eli Lilly is a thing of beauty.
That's me. Not diabetic or even close. But I just couldn't drop weight. Was already exercising frequently (lifting 4-5 times a week and playing soccer) but my portion control was terrible. Genetically, I'm screwed, too, as most of my extended family is/was obese. I get semaglutide from a local compounding pharmacy since my insurance doesn't cover Wegovy. It's been about 15 months now. I initially went from 256 to 216, but am now 223. The slight gain is actually muscle. I would actually like to drop another 10-15 but I'm finding I've hit a wall. Most days, I don't eat breakfast and either eat a small lunch and a decent dinner or a good lunch and don't eat dinner. I do eat more healthy but I also still indulge myself...just with much smaller portions than before.
Ex-actly. My portion control was just awful. I knew it was awful, but that didn't stop me. I've gone from about 296 to 213 in a year and a month. Slow, steady weight loss. Interestingly enough, I still snack overnight. Hence the slow part probably of the weight loss journey. But I eat so little in the day, that I think it still works out.
