Not sure about Pena, but I'd be shocked if Yordan isn't in the concussion protocol. Guess they could call up Perez again if Pena's out for a bit. Dubon and Diaz can handle the IF. Siri the OF. Dunno.
None as important as Yordan though. And none of them potentially inflicting as much damage as Yordan. Always have Carlos Lee/Adam Everett flashbacks