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Almost anyone in Raising Arizona. Frances McDormand as "Dot" John Goodman as "Gail" William Forsythe as "Evelle" Sam McMurray as "Glen" Randall Texx Cobb as the "Leonard Smalls" (aka Warthog from hell) Pete Postlethwaite (rip) as "Kobayashi" in Usual Suspects also comes to mind.
I don't know if it can be said enough times that Wayne's World 2 sucked. Like "Two Days in the Valley" compared to Pulp Fiction.
Danny DeVito playing a car wash owner who is addicted to gambling, in the cheesy 70's exploitation movie, "The Van".