Funny enough, it's hard to explain but i've been having these like weird warm pulsating feelings in my nasal cavity since I got Covid. Yeah I had a fever and still have chills too, but just wanted to note one of the many weird things your body does when you have Covid.
I read a pretty in depth article, and its been a while, so I don't know if I remember the details...part of the reason the AstraZeneca vaccine had worse efficacy is because they ran the trial differently. With the Moderna and Pfizer stage 3 trials, they only tested for positive cases when people got SICK. So if you never had any symptoms, you never got tests and you were put in the "effective" bucket, so there were most likely asymptomatic people that WOULD HAVE tested positive. With Astra Zeneca, they tested ALL participants for COVID, whether they were symptomatic or not. If you were asymptomatic, but had a positive test, you were put in the "sick" bucket. So AstraZeneca may be every bit as effective for keeping you from getting sick, but it's 62% effective from you getting the virus AT ALL...asymptomatic or not. Interestingly, this proves that AstraZeneca is effective at PREVENTING INFECTION, not just keeping you from getting sick. The article (in STAT, I think), went on to say that since all three of these vaccines are the same technology (basically), they probably all have very similar results. They probably ALL keep you ~62% from getting INFECTED, and they probably ALL keep 90-95% from getting SICK. The best, most under-rated news is that they ALL keep almost everyone out of the hospital and getting REALLY SICK (Moderna famously had 0 severe disease in the trial)
The mRNA vaccines target the Spike Protein on the virus. Not only that, they are all built to target multiple PARTS of the Spike Protein for more full coverage. The reason that most Doctors are not overly concerned about the virus escaping the mRNA vaccines is that: 1. This virus mutates pretty slowly as far as viruses mutate. 2. The spike protein would have to mutate 3. The spike protein would have to mutate MULTIPLE ways since the vaccines mimic MULTIPLE parts of the spike protein (or...make your body make proteins that mimic multiple parts). They purposely built this into the vaccines to cover mutations in the spike protein. So yes...down the road, we may need to get annual vaccines (or every 2-3 years), but they built in a couple years of coverage into these first vaccines. So they already covered "multiple strains" because they built in multiple ways to cover the spike protein.
Hopefully my parents are getting vaccinated on Saturday. Our GM for our UPS Stores found https://www.facebook.com/FMROT/ and their registration link. They are doing vaccinations in Dripping Springs on Saturday between 12-6. If you are in the Austin area and want to try to get in give them a call.
Good thanx for the info. The Sputnik also requires to abstain from alcohol for ..2 months so there's that. But that anyway shouldn't be available here or over there in the first place. The chinese Sinovac has only 50% effectiveness according to the last trial in Brazil. I wonder what kind of vaccines the Johnson, Curevac and whatever else we are waiting for are. About the gap between the doses: the UK NHS has been forced by reality to change it to 12 weeks which is fine for the AstraZeneca. But Pfizer immediately protested that they have no data/proof that their vaccine offers immunity with such a large time gap between doses. Also there is even talk over there about just skipping the second dose and give to as many people the first dose.
On a review of systems the true are treated pretty synonymously sometimes spoken as one word “any feverchills”?
Is this for nursing homes folks? If not I’m pretty sure this first phase is only for frontline health (they’ve been too liberal with this imo) and very high risk pts. we need to make sure those at highest risk for mortality get it first. Do hope you parents also are able to obtain it
My mom decided to wait but my dad is in about the highest risk as you can get (80, heart disease, prior cancer). I called the group and they are doing the vaccinations at the main fire station in dripping springs so I have no idea if it’s for nursing homes. The guy said he should be able to get my dad in for the shot.
Tough call. https://yourlocalepidemiologist.com/delayed-second-dose/ ... However, yesterday the UK made waves by announcing that they are prioritizing first doses. In other words, people won’t get their second dose of AstraZeneca or Pfizer until up to 3 months after their first dose. This is a bold approach… give as many people their first dose as fast as possible (rather than providing two doses to fewer people). Some places in Canada have been doing this and Belgium is considering it too. ...
Honestly, not sure how Texas is going to prioritize 1B, because anyone 18+ with health condition might as well be anyone 18+ making up a health condition. I don't believe any place will require a doctor's note for medical history. It's gonna be a long time before people get vaccines at the rate we are going.
