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COVID-19 (coronavirus disease)/SARS-CoV-2 virus

Discussion in 'BBS Hangout' started by tinman, Jan 22, 2020.

  1. txtony

    txtony Member

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    not sure what to think of this...

     
  2. EddieWasSnubbed

    EddieWasSnubbed Contributing Member

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    Good idea. We need to go paperless in my job as well. A lot of people want it, but there's too many old fogies around to make it happen. Some people just couldn't figure it out.
     
    CCity Zero likes this.
  3. asianballa23

    asianballa23 Member

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    basically make your own mask, just dont buy one so the medical staff will have enough
     
  4. hooroo

    hooroo Member

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    https://www.eurekalert.org/pub_releases/2020-04/mu-pcd040320.php
    • Australian Scientists have shown that an anti-parasitic drug already available around the world can kill the virus within 48 hours.


    • Scientists from Monash University in Melbourne showed that a single dose of the drug, Ivermectin, could stop the SARS-CoV-2 virus growing in cell culture - effectively eradicating all genetic material of the virus within 48 hours.


    • The next steps are to determine the correct human dosage - ensuring the doses shown to effectively treat the virus in the test tube are safe levels for humans.


    • The use of Ivermectin to combat COVID-19 depends on pre-clinical testing and clinical trials, with funding urgently required to progress the work.


    • Ivermectin is an FDA-approved anti-parasitic drug that has also been shown to be effective in vitro against a broad range of viruses including HIV, Dengue, Influenza and Zika virus.


    • The findings of the study were published today in Antiviral Research.


    A collaborative study led by Monash University's Biomedicine Discovery Institute (BDI) in Melbourne, Australia, with the Peter Doherty Institute of Infection and Immunity (Doherty Institute), has shown that an anti-parasitic drug already available around the world kills the virus within 48 hours.

    The Monash Biomedicine Discovery Institute's Dr Kylie Wagstaff, who led the study, said the scientists showed that the drug, Ivermectin, stopped the SARS-CoV-2 virus growing in cell culture within 48 hours.

    "We found that even a single dose could essentially remove all viral RNA by 48 hours and that even at 24 hours there was a really significant reduction in it," Dr Wagstaff said.

    Ivermectin is an FDA-approved anti-parasitic drug that has also been shown to be effective in vitro against a broad range of viruses including HIV, Dengue, Influenza and Zika virus.

    Dr Wagstaff cautioned that the tests conducted in the study were in vitro and that trials needed to be carried out in people.

    "Ivermectin is very widely used and seen as a safe drug. We need to figure out now whether the dosage you can use it at in humans will be effective - that's the next step," Dr Wagstaff said.

    "In times when we're having a global pandemic and there isn't an approved treatment, if we had a compound that was already available around the world then that might help people sooner. Realistically it's going to be a while before a vaccine is broadly available.

    Although the mechanism by which Ivermectin works on the virus is not known, it is likely, based on its action in other viruses, that it works to stop the virus 'dampening down' the host cells' ability to clear it, Dr Wagstaff said.

    Royal Melbourne Hospital's Dr Leon Caly, a Senior Medical Scientist at the Victorian Infectious Diseases Reference Laboratory (VIDRL) at the Doherty Institute where the experiments with live coronavirus were conducted, is the study's first author.

    "As the virologist who was part of the team who were first to isolate and share SARS-COV2 outside of China in January 2020, I am excited about the prospect of Ivermectin being used as a potential drug against COVID-19," Dr Caly said.

    Dr Wagstaff made a previous breakthrough finding on Ivermectin in 2012 when she identified the drug and its antiviral activity with Monash Biomedicine Discovery Institute's Professor David Jans, also an author on this paper. Professor Jans and his team have been researching Ivermectin for more than 10 years with different viruses.

    Dr Wagstaff and Professor Jans started investigating whether it worked on the SARS-CoV-2 virus as soon as the pandemic was known to have started.

    The use of Ivermectin to combat COVID-19 would depend on the results of further pre-clinical testing and ultimately clinical trials, with funding urgently required to keep progressing the work, Dr Wagstaff said.

    ###

    Read the full paper in Antiviral Research titled: The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro: https://www.sciencedirect.com/science/article/pii/S0166354220302011
     
  5. Icehouse

    Icehouse Contributing Member

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  6. cheke64

    cheke64 Member

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    I hear so many times that there's a vaccine a cure and then it disappears
     
  7. Bandwagoner

    Bandwagoner Contributing Member

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    I've used that on cows. You can buy it at Tractor Supply.
     
    malakas likes this.
  8. Dr of Dunk

    Dr of Dunk Clutch Crew

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    That's because you're reading things wrong. :D
    Possible cure in medicine usually doesn't mean you start handing it out to everybody as a cure. It'll take months of trials to get anything viable. This is so people aren't getting killed by the "cure". There are several drugs in multi-stage clinical trials now that take months for approval. Some will fail along the way in one of those steps. Others may succeed. If you're looking for an actual vaccine, which hopefully stop you from catching the virus in the first place, then you're probably not going to get anything until the end of the year or early next year at the earliest unless there's a miracle. Then there're the ones looking for a treatment. Those are like the ones hooroo posted above that treat you after you've gotten it. There are probably 30-40 of these drugs in some stage of trial out there.

    As far as I know, among the vaccines, Moderna's vaccine is probably the furthest ahead in American trials.
    Among the treatments, Gilead's Remdesivir is probably the furthest ahead (we may know something about it soon -- whether positive or negative within in the next couple of weeks from the last I heard a report on tv).

    No matter what the initial reports of "cure" or "possible cure", they're not going to just get thrown out there within a day or two.
     
    CCity Zero, malakas, jboslett and 2 others like this.
  9. Dr of Dunk

    Dr of Dunk Clutch Crew

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    Great. Now you went and did it ...
     
    Ziggy likes this.
  10. Dr of Dunk

    Dr of Dunk Clutch Crew

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    Not trying to turn this thread political, but along the same lines, for those in the small business fund boat :

     
    Ziggy, ArtV, NotInMyHouse and 2 others like this.
  11. Bandwagoner

    Bandwagoner Contributing Member

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  12. opticon

    opticon Member

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    Yet another reason to hate BoA. They are the scum of the Earth.
     
  13. PhiSlammaJamma

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    Isn't it ironic though. He's the one who is leaving for dry land.

    I understand both sides. But the Military shows little to no humanity and when you enter, I am pretty sure everyone knows it. They get the job done for sure. But at the expense of their team. Except for that whole never leave anyone behind stuff, which is pretty cool, but damn it, run into the biological gas for us first.
     
    EddieWasSnubbed likes this.
  14. Major

    Major Member

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    There are something like 1000 SBA Lenders. Most of them are going to take care of their own customers first. This is nothing specific to BoA.
     
    Hakeemtheking likes this.
  15. Exiled

    Exiled Member

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    a new project suggestion for @CCity Zero

    an old car from junk yard hooked up to shop vacuum, what's could possibly go wrong?

     
    CCity Zero likes this.
  16. donkeypunch

    donkeypunch Contributing Member

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  17. CCity Zero

    CCity Zero Member

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    Thanks for sharing this video! I enjoy seeing stuff like this, it got me a bit curious when you mentioned this - check this out:

    http://blog.modernmechanix.com/diy-iron-lung/

    We could possibly make one with a newer design! Haha
     
    Exiled likes this.
  18. Exiled

    Exiled Member

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    I really felt this could give Dodge/Fiat a new life
     
    CCity Zero likes this.
  19. CCity Zero

    CCity Zero Member

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    Hahah, that's great, seriously laughing at the thought of picking up a dodge/fiat, "oh.. no, we just need the metal, the other stuff isn't needed, we're making something better" haha
     
    Exiled likes this.
  20. Senator

    Senator Member

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    The specialized infectious disease hospital in south Italy has procedures and barriers to transmission that has not only resulted in 0 doctor nurse deaths, but 0 infections as well. Compare that to the 60 deaths of medical professionals in the north... just winging it. Following "general" guidelines.

    I realize this is America and you can't construct specialized facilities overnight, but it shows how lab rat the education system is here when it comes to solving real time problems. Far more obsessed with bureaucracy and political mind games than getting things done, and it's been this way for 2 decades now.
     
    Richie_Rich, BallaDoc and CCity Zero like this.
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